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Data Set Group: GSE16780 UCLA Hybrid MDP Liver Affy HT M430A (Sep11) modify this page

Data Set: GSE16780 UCLA Hybrid MDP Liver Affy HT M430A (Sep11) RMA modify this page
GN Accession: GN373
GEO Series: GSE16780
Title: Hybrid Mouse diversity Panel Liver Expression Profile
Organism: Mouse (mm10)
Group: BXD
Tissue: Liver mRNA
Dataset Status: Public
Platforms: Affy Mouse Genome 430A, 430B, 430A 2.0 (GPL339,GPL340)
Normalization: RMA
Contact Information
Aldons Lusis
University of California, Los Angeles
UCLA Med-Cardio/Microbio BOX 951679
Los Angeles, CA 90095 USA
Tel. 310 825-1359
jlusis@mednet.ucla.edu
Website
Download datasets and supplementary data files

Specifics of this Data Set:
None

Summary:

Novel, systems-based approach to mouse genetics.



About the cases used to generate this set of data:

For complete information please refer to Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, Kirchgessner T, Pan C, Castellani LW, Kostem E, Furlotte N, Drake TA, Eskin E, Lusis AJ (2010) A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Research 20:281-90 PMID: 20054062



About the tissue used to generate this set of data:

Hybrid Mouse diversity Panel Liver Expression Profile



About the array platform:

Platform GPL8759 [HT_MG-430A] Affymetrix HT Mouse Genome 430A Array

The probe sets were selected from sequences derived from GenBank®, dbEST and RefSeq. The sequence clusters were created from the UniGene database (Build 107, June 2002) and then refined by analysis and comparison with the publicly available draft assembly of the mouse genome from the Whitehead Institute Center for Genome Research (MSCG, April 2002).

Oligonucleotide probes complementary to each corresponding sequence are synthesized in situ on the array. Eleven pairs of oligonucleotide probes, including a perfect match and mismatch probe, are used to measure the level of transcription of each sequence represented on the GeneChip® HT Mouse Genome 430 Array Plate Set.



About data values and data processing:

For complete information please refer to A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res 2010 Feb;20(2):281-90. PMID: 20054062



Notes:

Raw data provided as supplementary file at GEO Series GSE16780



Experiment Type:

Expression profiling by array.

Expression Profiles from 99 strains of inbred and recombinant inbred mice. Most assayed in triplicate. Two of 288 chips were excluded from the final analysis due to low QC scores.



Contributor:

Bennett BJ, Ghazalpour A



Citation:

Bennett BJ, Farber CR, Orozco L, Kang HM et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res 2010 Feb;20(2):281-90. PMID: 20054062



Data source acknowledgment:

Bennett BJ, Ghazalpour A



Study Id:
136

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