WebQTL
 
   |    Home    |    Search    |    Help    |    News    |    References    |    Policies    |    Links    |    Welcome! Login   

Data Set Group: UCLA BHF2 Liver (June05) mlratio modify this page

Data Set: UCLA BHF2 Liver (June05) mlratio modify this page
GN Accession: GN167
GEO Series: GSE2814
Title: Expression profiling of liver tissue from (C57BL/6J X C3H/HeJ)F2 mice on ApoE null backgrounds
Organism: Mouse (mm10)
Group: BHF2
Tissue: Liver mRNA
Dataset Status: Private
Platforms: Agilent Mouse Custom (GPL2510)
Normalization: mlratio
Contact Information
Aldons Lusis
University of California, Los Angeles
UCLA Med-Cardio/Microbio BOX 951679
Los Angeles, CA 90095 USA
Tel. 310 825-1359
jlusis@mednet.ucla.edu
Website
Download datasets and supplementary data files

Specifics of this Data Set:
None

Summary:

The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age.



About the cases used to generate this set of data:


About the tissue used to generate this set of data:


About the array platform:


About data values and data processing:


Notes:


Experiment Type:

Livers from 311 F2 female and male mice (animals fed a high fat "Western" diet from 8-24 weeks of age.) derived from C57BL/6J and C3H/HeJ parental strains with both on ApoE null backgrounds. All samples were compared to a common pool created from equal portions of RNA from each of the samples. Keywords=Genetics of Gene Expression Keywords=C57BL/6J Keywords=C3H/HeJ



Contributor:


Citation:
  • Wang S, Yehya N, Schadt EE, Wang H et al. Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity. PLoS Genet 2006 Feb;2(2):e15. PMID: 16462940
  • Yang X, Schadt EE, Wang S, Wang H et al. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res 2006 Aug;16(8):995-1004. PMID: 16825664
  • Ghazalpour A, Doss S, Zhang B, Wang S et al. Integrating genetic and network analysis to characterize genes related to mouse weight. PLoS Genet 2006 Aug 18;2(8):e130. PMID: 16934000
  • Chen Y, Zhu J, Lum PY, Yang X et al. Variations in DNA elucidate molecular networks that cause disease. Nature 2008 Mar 27;452(7186):429-35. PMID: 18344982
  • Wu S, Mar-Heyming R, Dugum EZ, Kolaitis NA et al. Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice. Hum Mol Genet2010 Feb 15;19(4):597-608. PMID: 19995791
  • van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS et al. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics2010 Jul;185(3):1059-68. PMID: 20439777


Data source acknowledgment:


Study Id:
49

CITG WWW service initiated January, 1994 as The Portable Dictionary of the Mouse Genome and June 15, 2001 as WebQTL. This site is currently operated by Rob Williams, Pjotr Prins, Zachary Sloan, Arthur Centeno. Design and code by Pjotr Prins, Zach Sloan, Arthur Centeno, Danny Arends, Christian Fischer, Sam Ockman, Lei Yan, Xiaodong Zhou, Christian Fernandez, Ning Liu, Rudi Alberts, Elissa Chesler, Sujoy Roy, Evan G. Williams, Alexander G. Williams, Kenneth Manly, Jintao Wang, and Robert W. Williams, colleagues. Python Powered Registered with Nif
GeneNetwork support from:
  • The UT Center for Integrative and Translational Genomics
  • NIGMS Systems Genetics and Precision Medicine project (R01 GM123489, 2017-2021)
  • NIDA NIDA Core Center of Excellence in Transcriptomics, Systems Genetics, and the Addictome (P30 DA044223, 2017-2022)
  • NIA Translational Systems Genetics of Mitochondria, Metabolism, and Aging (R01AG043930, 2013-2018)
  • NIAAA Integrative Neuroscience Initiative on Alcoholism (U01 AA016662, U01 AA013499, U24 AA013513, U01 AA014425, 2006-2017)
  • NIDA, NIMH, and NIAAA (P20-DA 21131, 2001-2012)
  • NCI MMHCC (U01CA105417), NCRR, BIRN, (U24 RR021760)
    Join GeneNetwork Mailing List
    It took 0.038 second(s) for lily.uthsc.edu to generate this page