Summary: |
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About the cases used to generate this set of data: |
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About the tissue used to generate this set of data: |
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About downloading this data set: |
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About the array platform: |
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About data values and data processing: |
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Data source acknowledgment: |
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Experiment Type: |
| Expression profiling by array |
Overall Design: |
| Information about the genes that are preferentially expressed during the course of Alzheimer's disease (AD) could improve our understanding of the molecular mechanisms involved in the pathogenesis of this common cause of cognitive impairment in older persons, provide new opportunities in the diagnosis, early detection, and tracking of this disorder, and provide novel targets for the discovery of interventions to treat and prevent this disorder. Information about the genes that are preferentially expressed in relationship to normal neurological aging could provide new information about the molecular mechanisms that are involved in normal age-related cognitive decline and a host of age-related neurological disorders, and they could provide novel targets for the discovery of interventions to mitigate some of these deleterious effects. |
Contributor: |
| Stephan DA, Liang WS |
Citation: |
| Liang WS, Dunckley T, Beach TG, Grover A et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics 2007 Feb 12;28(3):311-22. PMID: 17077275 |
Submission Date: |
| 10-Jul-06 |
Laboratory: |
| NIH Neuroscience Microarray Consortium |
Samples: |
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